IL-21 R / APC / 4A9

Citations: (2)
Product Details
Supplier BioLegend
Catalog #: 131909 (View supplier product page)
Size 25 μg
Price $142.00
Antigen IL-21 R
Clone 4A9
Host Rat
Isotype IgG2a κ
Conjugate APC
Target Species Mouse
Applications FC
Description APC anti-mouse IL-21R
About IL-21 R and APC
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Images
  IL-21 R APC BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:4A9

C57BL/6 splenocytes stained with 4A9 APC

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Reviews & Ratings
APC Excitation and Emission Spectra