CCR6 / Brilliant Violet 421 / 29-2L17
CCR6 / Brilliant Violet 421 / 29-2L17
Citations:
(15)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 129818 (View supplier product page) | |
| Size | 500UL | |
| Price | $407.00 | |
| Antigen | CCR6 | |
| Clone | 29-2L17 | |
| Host | Armenian Hamster | |
| Isotype | IgG | |
| Conjugate | Brilliant Violet 421 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Brilliant Violet 421 anti-mouse CD196 (CCR6) |
About CCR6 and Brilliant Violet 421
| CCR6 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Brilliant Violet 421 | Brilliant™ Violet 421 (BV421) is a Violet-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 450/50 bandpass filter. BV421 has an excitation peak at 405 nm and an emission peak at 421 nm, and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. Other similar fluorophores include SuperNova V428 (Beckman Coulter), StarBright Violet 440 (Bio-Rad) and SuperBright 436 (Thermo Fisher). BV421 is very bright and is most commonly used for flow cytometry. BV421 is very photo- and fixative stable. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dyes from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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C57BL/6 splenocytes were stained with CD45R/B220 FITC and CD196 (CCR6) (clone 29-2L17) Brilliant Violet 421 (top) or Armenian Hamster IgG Brilliant Violet 421™ isotype control (bottom) |
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Citations
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Reviews & Ratings
Brilliant Violet 421 Excitation and Emission Spectra
$407.00
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