COX4I1 / Unconjugated /
COX4I1 / Unconjugated /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C413515 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | COX4I1 | |
Clone | ||
Host | Mouse | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human, Mouse, Rat | |
Applications | ICC, IF, WB | |
Description | COXIV / COX4 Antibody |
About COX4I1 and Purified
COX4I1 | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
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