CD357 / Biotin / DTA-1

Citations: (2)
Product Details
Supplier BioLegend
Catalog #: 126305 (View supplier product page)
Size 50 μg
Price $147.00
Antigen CD357
Clone DTA-1
Host Rat
Isotype IgG2b κ
Conjugate Biotin
Target Species Mouse
Applications FC
Description Biotin anti-mouse CD357 (GITR)
About CD357 and Biotin
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
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Biotin Excitation and Emission Spectra