EMI1 / Unconjugated / EMI1/1176
EMI1 / Unconjugated / EMI1/1176
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C390162 (View supplier product page) | |
Size | 100 μg | |
Price | $560.00 | |
Antigen | EMI1 | |
Clone | EMI1/1176 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | FC, IF, IHC, IHC-P, WB | |
Description | FBXO5 / EMI1 Antibody (aa1-250, clone EMI1/1176, Azide-free) |
About EMI1 and Purified
EMI1 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008] |
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