Alkaline Phosphatase / Unconjugated / TRA-2-49/6E
Alkaline Phosphatase / Unconjugated / TRA-2-49/6E
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C38190 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | Alkaline Phosphatase | |
| Clone | TRA-2-49/6E | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Feline, Human, Monkey, Porcine, Rabbit | |
| Applications | FC, IF, IP | |
| Description | ALPL / Alkaline Phosphatase Antibody (clone TRA-2-49/6E) |
About Alkaline Phosphatase and Purified
| Alkaline Phosphatase | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015] |
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Citations
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