Nectin-4 / Unconjugated /
Nectin-4 / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C37484 (View supplier product page) | |
| Size | 100 μg | |
| Price | $826.00 | |
| Antigen | Nectin-4 | |
| Clone | ||
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | ELISA, WB | |
| Description | PVRL4 / Nectin 4 Antibody |
About Nectin-4 and Purified
| Nectin-4 | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011] |
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Citations
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