ACK1 / Unconjugated /
ACK1 / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C357153 (View supplier product page) | |
| Size | 100 μl | |
| Price | $391.00 | |
| Antigen | ACK1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | IF, IHC, IHC-P, WB | |
| Description | TNK2 / ACK1 Antibody (phospho-Tyr284) |
About ACK1 and Purified
| ACK1 | This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008] |
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Citations
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