CD44 / PE / IM7

Citations: (81)
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Product Details
Supplier BioLegend
Catalog #: 103007 (View supplier product page)
Size 50 μg
Price $56.00
Antigen CD44
Clone IM7
Host Rat
Isotype IgG2b κ
Conjugate PE
Target Species Human, Mouse
Applications FC
Description PE anti-mouse/human CD44
About CD44 and PE
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CD44 PE BioLegend antibody anti target:Human, Mouse host:Rat isotype:IgG2b κ clone:IM7

C57BL/6 mouse splenocytes stained with IM7 PE

  CD44 PE BioLegend antibody anti target:Human, Mouse host:Rat isotype:IgG2b κ clone:IM7

Human peripheral blood lymphocytes stained with IM7 PE

Citations
PE Excitation and Emission Spectra