UBE2D2 / Unconjugated / 3H1
UBE2D2 / Unconjugated / 3H1
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C340026 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | UBE2D2 | |
| Clone | 3H1 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB | |
| Description | UBE2D2 / UBCH5B Antibody (clone 3H1) |
About UBE2D2 and Purified
| UBE2D2 | Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] |
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Citations
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