CAMLG / Unconjugated / 1H3
CAMLG / Unconjugated / 1H3
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C337709 (View supplier product page) | |
| Size | 100 μl | |
| Price | $434.00 | |
| Antigen | CAMLG | |
| Clone | 1H3 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | FC, IF, WB | |
| Description | CAMLG / CAML Antibody (clone 1H3) |
About CAMLG and Purified
| CAMLG | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008] |
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Citations
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