EphB2 / Unconjugated /
EphB2 / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C330433 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | EphB2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | ELISA, IHC, WB | |
| Description | EPHB2 / EPH Receptor B2 Antibody (aa103-133) |
About EphB2 and Purified
| EphB2 | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
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Citations
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