IL-6 / PE / MQ2-6A3

Citations: (4)
Product Details
Supplier BD Biosciences
Catalog #: 551473 (View supplier product page)
Size 50 Tests
Price $180.00
Antigen IL-6
Clone MQ2-6A3
Host Rat
Isotype IgG2a κ
Conjugate PE
Target Species Cynomolgus macaque, Rhesus macaque
Applications FC
Description Hu/NHP IL-6 PE MQ2-6A3 50Tst
About IL-6 and PE
IL-6 This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

PE Excitation and Emission Spectra