GADD45A / Unconjugated /
GADD45A / Unconjugated /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C307629 (View supplier product page) | |
Size | 50 μg | |
Price | ||
Antigen | GADD45A | |
Clone | ||
Host | Mouse | |
Isotype | IgG | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | WB | |
Description | GADD45A / GADD45 Antibody |
About GADD45A and Purified
GADD45A | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010] |
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