FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C285001 (View supplier product page)
	Size	200 μl
	Price
	Antigen	RB1
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	PE
	Target Species	Human
	Applications	ELISA, FC, IHC, IP, WB
	Description	RB1 / Retinoblastoma / RB Antibody (C-Terminus, PE)

	RB1	The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

RB1 / PE /