CD49f / PE-Cy5 / GoH3

Citations: (48)
Product Details
Supplier BD Biosciences
Catalog #: 551129 (View supplier product page)
Size 100 Tests
Price $358.00
Antigen CD49f
Clone GoH3
Host Rat
Isotype IgG2a κ
Conjugate PE-Cy5
Target Species Canine, Human, Mouse, Porcine
Applications FC
Description Hu CD49f PE-Cy5 GoH3 100Tst
About CD49f and PE-Cy5
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
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PE-Cy5 Excitation and Emission Spectra