CD45 / APC / 30-F11

Citations: (48)
Product Details
Supplier BD Biosciences
Catalog #: 561018 (View supplier product page)
Size 25 μg
Price $74.00
Antigen CD45
Clone 30-F11
Host Rat
Isotype IgG2b κ
Conjugate APC
Target Species Mouse
Applications FC
Description Ms CD45 APC 30-F11 25ug
About CD45 and APC
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Reviews & Ratings
APC Excitation and Emission Spectra