CCR6 / PerCP-Cy5.5 / 11A9

Product Details
Supplier BD Biosciences
Catalog #: 560621 (View supplier product page)
Size 50 Tests
Price $294.00
Antigen CCR6
Clone 11A9
Host Mouse
Isotype IgG1 κ
Conjugate PerCP-Cy5.5
Target Species Baboon, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Hu/NHP CD196 (CCR6) PerCP-Cy5.5 50Tst
About CCR6 and PerCP-Cy5.5
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
PerCP-Cy5.5 PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710.
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PerCP-Cy5.5 Excitation and Emission Spectra