MAPK10 / PE /
MAPK10 / PE /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C262598 (View supplier product page) | |
Size | 200 μl | |
Price | ||
Antigen | MAPK10 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | PE | |
Target Species | Human, Mouse | |
Applications | ELISA, IHC, WB | |
Description | MAPK10 / JNK3 Antibody (aa1-30, PE) |
About MAPK10 and PE
MAPK10 | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |