SOD1 / ATTO 633 /
SOD1 / ATTO 633 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C231758 (View supplier product page) | |
Size | 100 μg | |
Price | ||
Antigen | SOD1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | ATTO 633 | |
Target Species | Bovine, Human, Mouse, Rat | |
Applications | ELISA, IHC, IHC-P, IP, WB | |
Description | SOD1 / Cu-Zn SOD Antibody (Atto 633) |
About SOD1 and ATTO 633
SOD1 | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020] | |
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ATTO 633 | ATTO 633 from ATTO-TEC has an excitation peak at 629 nm and an emission peak at 657 nm. ATTO 633 belongs to a new generation of fluorescent labels for the red spectral region. Characteristic features of the label are strong absorption, high fluorescence quantum yield, and high thermal and photo-stability. Thus ATTO 633 is highly suitable for single-molecule detection applications and high-resolution microscopy such as SIM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. In common with most ATTO-labels, absorption and fluorescence are independent of pH, at least in the range of pH 2 to 11, used in typical applications. ATTO 633 is a cationic dye. After coupling to a substrate the label carries a net electrical charge of +1. The label is moderately hydrophilic. |