Cav1.2 / ATTO 594 / S57-46
Cav1.2 / ATTO 594 / S57-46
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C231558 (View supplier product page) | |
| Size | 100 μg | |
| Price | $454.00 | |
| Antigen | Cav1.2 | |
| Clone | S57-46 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | ATTO 594 | |
| Target Species | Hamster, Human, Mouse, Rat | |
| Applications | ICC, IF, IHC, IP, WB | |
| Description | CACNA1C / Cav1.2 Antibody (aa1507-1733, clone S57-46, Atto 594) |
About Cav1.2 and ATTO 594
| Cav1.2 | This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012] | |
|---|---|---|
| ATTO 594 | ATTO 594 from ATTO-TEC has an excitation peak at 601 nm and an emission peak at 627 nm. ATTO 594 is a novel fluorescent label belonging to the class of rhodamine dyes. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high thermal and photo-stability, and excellent water solubility. Thus ATTO 594 is highly suitable for single-molecule detection applications and high-resolution microscopy such as PALM, dSTORM, STED etc. Additionally the dye highly qualifies to be applied in flow cytometry (FACS), fluorescence in-situ hybridization (FISH) and many more. ATTO 594 is very hydrophilic and shows a very good water solubility. After coupling to a substrate the label carries a net electrical charge of -1. |
Citations
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