HspB8 / Alk Phosphatase / 3C12-H11
HspB8 / Alk Phosphatase / 3C12-H11
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C231426 (View supplier product page) | |
| Size | 100 μg | |
| Price | $450.00 | |
| Antigen | HspB8 | |
| Clone | 3C12-H11 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alk Phosphatase | |
| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, IF, IHC, WB | |
| Description | HSPB8 / H11 / HSP22 Antibody (clone 3C12-H11, AP) |
About HspB8 and Alk Phosphatase
| HspB8 | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
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Citations
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