SLC12A1 / ATTO 565 /
SLC12A1 / ATTO 565 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C229733 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | SLC12A1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | ATTO 565 | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB | |
| Description | SLC12A1 / NKCC2 Antibody (aa33-55, Atto 565) |
About SLC12A1 and ATTO 565
| SLC12A1 | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010] | |
|---|---|---|
| ATTO 565 | ATTO 565 from ATTO-Tec Gmbh has an excitation peak at 563 nm and an emission peak at 592 nm. |
Citations
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