CACNB4 / ATTO 488 / S10-7
CACNB4 / ATTO 488 / S10-7
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C227664 (View supplier product page) | |
| Size | 100 μg | |
| Price | $454.00 | |
| Antigen | CACNB4 | |
| Clone | S10-7 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | ATTO 488 | |
| Target Species | Human, Mouse, Rat | |
| Applications | ICC, IF, IHC, IP, WB | |
| Description | CACNB4 Antibody (aa458-474, clone S10-7, Atto 488) |
About CACNB4 and ATTO 488
| CACNB4 | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016] | |
|---|---|---|
| ATTO 488 | ATTO 488 is from ATTO-Tec Gmbh has an excitation peak at 501 nm and an emission peak at 523 nm. |
Citations
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