Dnmt1 / ATTO 390 / 4G11-C7
Dnmt1 / ATTO 390 / 4G11-C7
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C227542 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | Dnmt1 | |
| Clone | 4G11-C7 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | ATTO 390 | |
| Target Species | Human, Mouse, Zebrafish | |
| Applications | ChIP, IHC, IP, WB | |
| Description | DNMT / DNMT1 Antibody (aa620-950, clone 4G11-C7, Atto 390) |
About Dnmt1 and ATTO 390
| Dnmt1 | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] | |
|---|---|---|
| ATTO 390 | ATTO 390 from ATTO-TEC has an excitation peak at 390 nm and an emission peak at 448 nm. It is a novel fluorescent label with a coumarin structure. Characteristic features of the label are high fluorescence quantum yield, large Stokes-shift, good photo-stability, and low molecular weight. |
Citations
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