Syntaxin / PE / SP-6
Syntaxin / PE / SP-6
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C227473 (View supplier product page) | |
| Size | 100 μg | |
| Price | ||
| Antigen | Syntaxin | |
| Clone | SP-6 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | PE | |
| Target Species | Human, Mouse, Rat | |
| Applications | IF, IHC, WB | |
| Description | STX / Syntaxin Antibody (clone SP-6, RPE) |
About Syntaxin and PE
| Syntaxin | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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