GLE1 / Unconjugated / 1D8
GLE1 / Unconjugated / 1D8
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C197306 (View supplier product page) | |
| Size | 100 μg | |
| Price | $423.00 | |
| Antigen | GLE1 | |
| Clone | 1D8 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, IF, WB | |
| Description | GLE1 Antibody (clone 1D8) |
About GLE1 and Purified
| GLE1 | This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Citations
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