CHRND / Unconjugated / 2B2
CHRND / Unconjugated / 2B2
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C196919 (View supplier product page) | |
Size | 100 μg | |
Price | $423.00 | |
Antigen | CHRND | |
Clone | 2B2 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | Unconjugated | |
Target Species | Human | |
Applications | ELISA, WB | |
Description | CHRND Antibody (clone 2B2) |
About CHRND and Purified
CHRND | The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
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