GLP-1R / DyLight 488 /
GLP-1R / DyLight 488 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C181910 (View supplier product page) | |
| Size | 100 μl | |
| Price | $457.00 | |
| Antigen | GLP-1R | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 488 | |
| Target Species | Human, Mouse | |
| Applications | ICC, IF, IHC, IHC-P, WB | |
| Description | GLP1R / GLP-1 Receptor Antibody (DY488) |
About GLP-1R and DyLight 488
| GLP-1R | This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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