BLNK / Unconjugated / 5G9
BLNK / Unconjugated / 5G9
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C169382 (View supplier product page) | |
| Size | 100 μl | |
| Price | $436.00 | |
| Antigen | BLNK | |
| Clone | 5G9 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, FC, IF, IHC, IHC-P, WB | |
| Description | BLNK Antibody (clone 5G9) |
About BLNK and Purified
| BLNK | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |
|---|
Citations
| Additional Sources |
|
|---|
