Urokinase / Unconjugated /
Urokinase / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C150948 (View supplier product page) | |
| Size | 1 ml | |
| Price | $394.00 | |
| Antigen | Urokinase | |
| Clone | ||
| Host | Sheep | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | PLAU / Urokinase / uPA Antibody |
About Urokinase and Purified
| Urokinase | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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Citations
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