Mortalin / DyLight 550 /
Mortalin / DyLight 550 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C143572 (View supplier product page) | |
Size | 100 μl | |
Price | $416.00 | |
Antigen | Mortalin | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | DyLight 550 | |
Target Species | Human, Mouse | |
Applications | ICC, IF, IHC, IHC-P, WB | |
Description | LAMTOR3 / MP1 Antibody (aa20-180, DY550) |
About Mortalin and DyLight 550
Mortalin | This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] | |
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DyLight 550 | DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications. |