PUMA / DyLight 488 /
PUMA / DyLight 488 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C142275 (View supplier product page) | |
| Size | 100 μl | |
| Price | $457.00 | |
| Antigen | PUMA | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 488 | |
| Target Species | Human | |
| Applications | WB | |
| Description | BBC3 / PUMA Antibody (C-Terminus, DY488) |
About PUMA and DyLight 488
| PUMA | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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