NOD2 / DyLight 650 /
NOD2 / DyLight 650 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C142269 (View supplier product page) | |
Size | 100 μl | |
Price | $457.00 | |
Antigen | NOD2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | DyLight 650 | |
Target Species | Human, Monkey | |
Applications | WB | |
Description | NOD2 / CARD15 Antibody (C-Terminus, DY650) |
About NOD2 and DyLight 650
NOD2 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] | |
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DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |