FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C142129 (View supplier product page)
	Size	100 μl
	Price	$457.00
	Antigen	GAPDH
	Clone	2D4A7
	Host	Mouse
	Isotype	IgG1
	Conjugate	DyLight 650
	Target Species	Human, Mouse
	Applications	ELISA, IF, IHC, IHC-P, WB
	Description	GAPDH Antibody (clone 2D4A7, DY650)

	GAPDH	This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
	DyLight 650	DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

GAPDH / DyLight 650 / 2D4A7