NOD2 / DyLight 550 / 2D9
NOD2 / DyLight 550 / 2D9
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C141157 (View supplier product page) | |
Size | 100 μl | |
Price | $416.00 | |
Antigen | NOD2 | |
Clone | 2D9 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | DyLight 550 | |
Target Species | Human | |
Applications | IHC, IHC-P, IP, WB | |
Description | NOD2 / CARD15 Antibody (aa28-301, clone 2D9, DY550) |
About NOD2 and DyLight 550
NOD2 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] | |
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DyLight 550 | DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications. |