JARID2 / DyLight 488 /
JARID2 / DyLight 488 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C140930 (View supplier product page) | |
| Size | 100 μl | |
| Price | $457.00 | |
| Antigen | JARID2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 488 | |
| Target Species | Human, Mouse | |
| Applications | WB | |
| Description | JARID2 / JMJ Antibody (N-Terminus, DY488) |
About JARID2 and DyLight 488
| JARID2 | This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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