Perforin / Biotin / delta G9
Perforin / Biotin / delta G9
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C134747 (View supplier product page) | |
| Size | 100 μg | |
| Price | $544.00 | |
| Antigen | Perforin | |
| Clone | delta G9 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | FC, IHC, IHC-Fr | |
| Description | PRF1 / Perforin Antibody (clone delta G9, Biotin) |
About Perforin and Biotin
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] |
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Citations
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