FGR / Unconjugated / 1B12
FGR / Unconjugated / 1B12
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C133193 (View supplier product page) | |
| Size | 100 μg | |
| Price | $423.00 | |
| Antigen | FGR | |
| Clone | 1B12 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, IHC, IHC-P, WB | |
| Description | FGR Antibody (clone 1B12) |
About FGR and Purified
| FGR | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
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Citations
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