ERCC2 / Unconjugated /
ERCC2 / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C112342 (View supplier product page) | |
| Size | 100 μl | |
| Price | $457.00 | |
| Antigen | ERCC2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Bat, Bovine, Drosophila, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rat, Xenopus, Zebrafish | |
| Applications | WB | |
| Description | ERCC2 / XPD Antibody (N-Terminus) |
About ERCC2 and Purified
| ERCC2 | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
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Citations
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