MAP4K4 / Unconjugated / 4H9E7
MAP4K4 / Unconjugated / 4H9E7
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C108875 (View supplier product page) | |
| Size | 100 μl | |
| Price | $432.00 | |
| Antigen | MAP4K4 | |
| Clone | 4H9E7 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Description | MAP4K4 Antibody (clone 4H9E7) |
About MAP4K4 and Purified
| MAP4K4 | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Citations
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