ACLY / Unconjugated /
ACLY / Unconjugated /
Citations:
(1)
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-B13453 (View supplier product page) | |
| Size | 50 μl | |
| Price | $460.00 | |
| Antigen | ACLY | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | IHC, IHC-P, IP, WB | |
| Description | ACLY / ATP Citrate Lyase Antibody (aa350-400) IHC-plus‚Ñ¢ |
About ACLY and Purified
| ACLY | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014] |
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Citations
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