V-type proton ATPase subunit F / Unconjugated / 5F10
V-type proton ATPase subunit F / Unconjugated / 5F10
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-B11773 (View supplier product page) | |
| Size | 100 μl | |
| Price | $485.00 | |
| Antigen | V-type proton ATPase subunit F | |
| Clone | 5F10 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | Unconjugated | |
| Target Species | Canine, Human, Monkey, Rat | |
| Applications | FC, IF, IHC, IHC-P, WB | |
| Description | ATP6V1F Antibody (clone 5F10) IHC-plus‚Ñ¢ |
About V-type proton ATPase subunit F and Purified
| V-type proton ATPase subunit F | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008] |
|---|
Citations
| Additional Sources |
|
|---|
