GRPR / Unconjugated /
GRPR / Unconjugated /
Citations:
(2)
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-A831 (View supplier product page) | |
| Size | 50 μg | |
| Price | $440.00 | |
| Antigen | GRPR | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Bat, Bovine, Canine, Hamster, Human, Monkey, Mouse, Porcine, Rat | |
| Applications | ICC, IHC, IHC-P | |
| Description | GRPR Antibody (Cytoplasmic Domain) IHC-plus‚Ñ¢ |
About GRPR and Purified
| GRPR | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008] |
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Citations
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