ADAMTS5 / Unconjugated /
ADAMTS5 / Unconjugated /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-A1540 (View supplier product page) | |
| Size | 50 μg | |
| Price | $440.00 | |
| Antigen | ADAMTS5 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Monkey | |
| Applications | IHC, IHC-P | |
| Description | ADAMTS5 Antibody (Internal) IHC-plus‚Ñ¢ |
About ADAMTS5 and Purified
| ADAMTS5 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016] |
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Citations
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