Nav1.5 / PE /
Nav1.5 / PE /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-A109660 (View supplier product page) | |
Size | 100 μl | |
Price | $650.00 | |
Antigen | Nav1.5 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | PE | |
Target Species | Canine, Equine, Human, Monkey, Mouse, Porcine, Rat | |
Applications | IHC, IHC-P | |
Description | SCN5A / Nav1.5 Antibody (Internal, PE) IHC-plus‚Ñ¢ |
About Nav1.5 and PE
Nav1.5 | The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | |
---|---|---|
PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |