Perforin Monoclonal / APC / dG9 (delta G9)

Citations: (7)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 17-9994-42 (View supplier product page)
Size 100 Tests
Price $428.00
Antigen Perforin
Clone dG9 (delta G9)
Host Mouse
Isotype IgG2b κ
Conjugate APC
Target Species Human, Porcine
Applications FC
Description Perforin Monoclonal Antibody (dG9 (delta G9)), APC, eBioscience
About Perforin and APC
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra