PARP1 (cleaved D214) Monoclonal / PE / HLNC4

Citations: (4)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 12-6668-42 (View supplier product page)
Size 100 Tests
Price $358.00
Antigen PARP1 (cleaved D214)
Clone HLNC4
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human
Applications FC
Description PARP1 (cleaved Asp214) Monoclonal Antibody (HLNC4), PE, eBioscience
About PARP1 (cleaved D214) and PE
PARP1 (cleaved D214) This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra