IRF-4 Monoclonal / PE-Cy7 / 3E4

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 25-9858-80 (View supplier product page)
Size 25 μg
Price $144.00
Antigen IRF-4
Clone 3E4
Host Rat
Isotype IgG1 κ
Conjugate PE-Cy7
Target Species Human, Mouse
Applications FC
Description IRF4 Monoclonal Antibody (3E4), PE-Cyanine7, eBioscience
About IRF-4 and PE-Cy7
IRF-4 The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
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PE-Cy7 Excitation and Emission Spectra