CD8b Monoclonal / PerCP-eFluor 710 / eBioH35-17.2 (H35-17.2)

Citations: (18)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 46-0083-82 (View supplier product page)
Size 100 μg
Price $366.00
Antigen CD8b
Clone eBioH35-17.2 (H35-17.2)
Host Rat
Isotype IgG2b κ
Conjugate PerCP-eFluor 710
Target Species Mouse
Applications FC
Description CD8b Monoclonal Antibody (eBioH35-17.2 (H35-17.2)), PerCP-eFluor 710, eBioscience
About CD8b and PerCP-eFluor 710
CD8b The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
PerCP-eFluor 710 PerCP-eFluor™ 710 (PerCP-eF710) is a red-emitting tandem fluorophore that combines PerCP and eF710. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, eF710, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-eF710 has an excitation peak at 482 nm and an emission peak at 710 nm, and is considered a slightly-red shifted but brighter alternative to PerCP-Cy5.5. This dye and associated products are mostly used for flow cytometry. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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PerCP-eFluor 710 Excitation and Emission Spectra